| Name | Group | Language of Origin | Languages of Use | Meaning/Translation or Related Words | US 2021 |
|---|
| Sheyla | Cecil/Cecilia | Latin | English | Words: blind | |
| Shianne | Cheyenne | Dakota | English | Words: unintelligible speakers | |
| Shiloh | Shiloh | Hebrew | English | tranquil | #581 |
| Shiloh | Shiloh | Hebrew | English | tranquil | #410 |
| Shima | Shima | Navajo | English | mother | |
| Shimea | Shimea | Hebrew | English | fame | |
| Shirel | Shirel | Hebrew | French, English | maybe God's song | |
| Shirley | Shirley | Old English | English | bright clearing | |
| Shmuel | Samuel/Samuela | Hebrew | English, Hebrew | Words: hear / God, powerful | |
| Shulamith | Sulamith | Hebrew | English | | |
| Shyann | Cheyenne | Dakota | English | Words: unintelligible speakers | |
| Shyanne | Cheyenne | Dakota | English | Words: unintelligible speakers | |
| Shyheim | Shyheim | Unknown | English | | |
| Shyla | Cecil/Cecilia | Latin | English | Words: blind | |
| Sibyl | Sibylle | Old Greek | English | | |
| Sid | Sidney/Sidney | Old French | English | | |
| Sidney | Sidney/Sidney | Old French | English | | |
| Sidney | Sidney/Sidney | Old French | English | | |
| Sidony | Sidonius/Sidonia | Latin | English | | |
| Siena | Siena | Italian | English | | #613 |
| Sienna | Siena | Italian | English | | #149 |
| Sierra | Sierra | Spanish | English | sierra, mountain range | #510 |
| Sigmund | Siegmund | Old High German | German, English | Words: victory / protection, protector | |
| Silas | Silvan/Silvana | Latin | English | Words: wood, forest | #91 |
| Simon | Simon/Simone | Hebrew | German, French, English | He (God) has heard | #247 |
| Sincere | Sincere | Latin | English | sincere | #600 |
| Sinclair | Sinclair | Old French | English | | |
| Siona | Siona | Unknown | English | | |
| Sione | John/Johanna | Hebrew | English, Maori | Yahweh is gracious | |
| Sissy | Cecil/Cecilia | Latin | English | Words: blind | |
| Sky | Sky | English | English | sky | #714 |
| Skye | Sky | English | English | sky | #429 |
| Skyla | Skylar/Skylar | Dutch | English | student, scholar | #629 |
| Skylar | Skylar/Skylar | Dutch | English | student, scholar | #74 |
| Skylar | Skylar/Skylar | Dutch | English | student, scholar | |
| Skyler | Skylar/Skylar | Dutch | English | student, scholar | #555 |
| Skyler | Skylar/Skylar | Dutch | English | student, scholar | #689 |
| Slade | Slade | Old English | English | valley | |
| Sloan | Sloan | Old Irish | English | descendant of Sluaghadhán | #574 |
| Sloane | Sloan | Old Irish | English | descendant of Sluaghadhán | #143 |
| Soleil | Soleil | French | English | sun | #996 |
| Solomon | Solomon/Salome | Hebrew | English | the peaceful | #421 |
| Soma | Soma | Unknown | English | | |
| Sommer | Summer | English | English | summer | |
| Sonia | Sophia | Old Greek | English | wisdom | |
| Sonny | Sonny | English | English | | #497 |
| Sophia | Sophia | Old Greek | German, Italian, English, Russian | wisdom | #6 |
| Sophus | Sophus | Old Greek | German, English | wise | |
| Soren | Severin/Severina | Latin | English | the severe | #537 |
| Spartacus | Spartaco | Latin | English | from Sparta | |
| Spencer | Spencer | Old French | English | dispenser of provisions | |
| Spencer | Spencer | Old French | English | dispenser of provisions | #315 |
| Spenser | Spencer | Old French | English | dispenser of provisions | |
| Spike | Spike | English | English | | |
| Spiridon | Spyridon | Old Greek | German, English | spirit | |
| Stacey | Eustachius/Eustacia | Old Greek | English | Words: good, well | |
| Stacey | Anastasius/Anastasia | Old Greek | English | resurrection | |
| Staci | Anastasius/Anastasia | Old Greek | English | resurrection | |
| Stacie | Anastasius/Anastasia | Old Greek | English | resurrection | |
| Stacy | Eustachius/Eustacia | Old Greek | English | Words: good, well | |
| Stacy | Anastasius/Anastasia | Old Greek | English | resurrection | |
| Stan | Stanley | Old English | English | stone clearing, stone meadow | |
| Stanislas | Stanislaw/Stanislava | Old Slavic | German, English, Latinized | Words: strength, firmness / fame, glory, Slav | |
| Stanislaus | Stanislaw/Stanislava | Old Slavic | German, English, Latinized | Words: strength, firmness / fame, glory, Slav | |
| Stanley | Stanley | Old English | English | stone clearing, stone meadow | #790 |
| Star | Star | English | English | star | |
| Starr | Star | English | English | star | |
| Steeven | Steven/Stephanie | Old Greek | English | the crowned | |
| Steevy | Steven/Stephanie | Old Greek | English | the crowned | |
| Stella | Stella | Latin | German, Italian, English | star | #41 |
| Stephanie | Steven/Stephanie | Old Greek | German, English | the crowned | #454 |
| Stephany | Steven/Stephanie | Old Greek | English | the crowned | |
| Stephen | Steven/Stephanie | Old Greek | English | the crowned | #341 |
| Stephi | Steven/Stephanie | Old Greek | English | the crowned | |
| Stephon | Steven/Stephanie | Old Greek | English | the crowned | |
| Sterling | Sterling | Old English | English | little star | #382 |
| Stetson | Stetson | Unknown | English | | #371 |
| Steve | Steven/Stephanie | Old Greek | English | the crowned | |
| Steven | Steven/Stephanie | Old Greek | Dutch, English | the crowned | #235 |
| Stevie | Steven/Stephanie | Old Greek | English | the crowned | #284 |
| Stevie | Steven/Stephanie | Old Greek | English | the crowned | |
| Stewart | Stewart | Old English | English | guardian of the home | |
| Stone | Stone | English | English | stone | |
| Storm | Storm | English | English | storm | |
| Stormi | Stormy | English | English | stormy | #928 |
| Stormy | Stormy | English | English | stormy | |
| Stuart | Stewart | Old English | English, Scottish | guardian of the home | |
| Sue | Susanne | Hebrew | English | lily | |
| Sufyan | Sufyan | Arabic | English, Arabic | | |
| Sulayman | Solomon/Salome | Hebrew | English, Arabic | the peaceful | |
| Suleiman | Solomon/Salome | Hebrew | English, Turkish, Arabic | the peaceful | |
| Süleyman | Solomon/Salome | Hebrew | English, Turkish, Arabic | the peaceful | |
| Sullivan | Sullivan | Old Irish | English, Irish | | #372 |
| Summer | Summer | English | English | summer | #141 |
| Sunny | Sunny | English | English | sunny | #649 |
| Susan | Susanne | Hebrew | English | lily | |
| Susanne | Susanne | Hebrew | German, English | lily | |
| Susie | Susanne | Hebrew | English | lily | |
| Sutton | Sutton | Old English | English | south town | #540 |
| Sutton | Sutton | Old English | English | south town | #244 |
